Coenzyme Q10

Coenzyme Q10 Effects on Hypertension (High Blood Pressure)

Coenzyme Q10

Coenzyme Q10

 Coenzyme Q10 belongs to a family of substances called ubiquinones.  Coenzyme Q10 benefits include antioxidant activity in the mitochondria protecting against per oxidation of lipid membranes. Some patients, especially those with migraines, asthma, hypertension and allergies may have an inborn or acquired error of metabolism that prevents them from making sufficient amounts of coenzyme Q10. Coenzyme Q10 benefits appear to be helpful in the management of cardiovascular disease and hypertension and in Japan CoQ10  has been approved as a drug for use in congestive heart failure since 1974. Hypertension is a risk factor for coronary heart disease, stroke, kidney failure, and peripheral vascular disease. Lowering high blood pressure can decrease the risk of developing these diseases. Many dietary and lifestyle modifications have been shown to be effective for lowering blood pressure including weight loss, regular exercise, limiting salt and alcohol intake, increasing fruits, vegetables and reducing stress levels. Adding potassium, calcium, magnesium, and fish oils has also been found to be beneficial in some cases. Because anti-hypertensive drugs frequently cause side effects, alternative treatments for hypertension may be needed to achieve satisfactory blood pressure reduction. 

Coenzyme Q10 Benefits and Research

Coenzyme Q10  (CoQ10) is a compound that is made in the body and is present in small quantity in some foods. coenzyme Q10 has been found to lower blood pressure in five different studies of hypertension. The coenzyme Q10 assessment was found to be lower in 59 patients with essential hypertension. In clinical trials supplementing coenzyme Q10 produced a substantial decrease in blood pressure in patients with essential hypertension that was seen after one to four months of supplementation.  The average systolic blood pressure decreased from 165 mm Hg to 147 mm Hg while the average diastolic blood pressure decreased from 98 mmHg to 86 mm Hg. The fall in blood pressure also contributed to a significant decrease in peripheral arterial resistance. Consideration with coenzyme Q10 should be made for those patients who do not respond to diet or life-style changes, but should do so under the supervision of their doctor.

This article on Coenzyme Q10 is informational and not to be used to diagnose or treat any medical condition

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